carcinoid syndrome is an abnormality that occurs when a small tumor (Carcinoid tumors) produce chemicals that enter the bloodstream. Chemicals cause these symptoms. Slow-growing tumors are mainly found in the gastrointestinal tract and lungs (bronchi), occur most commonly in the appendix and frequently in the small intestine (20%); rectum (15%); trachea (12%), esophagus, stomach and colon (10%); and ovaries, biliary tract, and pancreas (3%). When the tumor has spread and caused this symptom The disease is rare and occurs in about 3 out of 100,000 people.