Cancer refers to the growth of abnormal cells in the body. Vaginal cancer refers to the growth of cancer cells in the vagina. The vagina is the tube that connects the uterus to the genitals. This type of cancer usually develops in the cells lining the vagina. This rare cancer affects 1 in 200,000 women and occurs primarily after menopause. (Change of life) The average age is 60 years. Cancer can spread to nearby organs or parts of the body through the bloodstream or lymphatic system.